Cancer metabolism: the Warburg effect today.
نویسنده
چکیده
One of the first studies on the energy metabolism of a tumour was carried out, in 1922, in the laboratory of Otto Warburg. He established that cancer cells exhibited a specific metabolic pattern, characterized by a shift from respiration to fermentation, which has been later named the Warburg effect. Considerable work has been done since then, deepening our understanding of the process, with consequences for diagnosis and therapy. This review presents facts and perspectives on the Warburg effect for the 21st century.
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عنوان ژورنال:
- Experimental and molecular pathology
دوره 89 3 شماره
صفحات -
تاریخ انتشار 2010